Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199246 | 0.95 | GAA (0.49) | ALDH1A1LMNAGAAMAPTKDM4E | |
| SCHEMBL9199902 | 0.92 | GAA (0.47) | ALDH1A1LMNAGAATSHRSMN1; SMN2 | |
| SCHEMBL8352131 | 0.91 | GAA (0.43) | ALDH1A1LMNAGAATSHRSMN1; SMN2 | |
| SCHEMBL10577527 | 0.91 | ALDH1A1 (0.45) | ALDH1A1LMNATSHRSMN1; SMN2MAPT | |
| SCHEMBL8354999 | 0.91 | GAA (0.43) | ALDH1A1LMNAGAATSHRSMN1; SMN2 | |
| SCHEMBL9441836 | 0.88 | GAA (0.43) | ALDH1A1LMNAGAATSHRSMN1; SMN2 | |
| SCHEMBL9195558 | 0.87 | GAA (0.53) | ALDH1A1GAAMAPTKDM4ECDK1 | |
| SCHEMBL10720416 | 0.85 | ALDH1A1 (0.42) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL8355019 | 0.85 | GAA (0.47) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL8358886 | 0.85 | GAA (0.47) | ALDH1A1LMNAGAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087780-B2 | Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof | NISSAN CHEMICAL IND LTD (JP) | 1995-02-15 | — | — | EP | claimed |