SCHEMBL8352131

SCHEMBL8352131

CCOC(=O)c1c(Cl)nn(C)c1S(=O)(=O)NC(=O)Nc1nc(C)cc(OC)n1

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.43
ALDH1A1 P00352 3/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.40
TSHR P16473 2/20 0.39
POLB P06746 1/20 0.38
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
CDK1 P06493 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9441836 0.97 GAA (0.43) GAAALDH1A1LMNASMN1; SMN2TSHR
SCHEMBL8358886 0.95 GAA (0.47) GAAALDH1A1LMNASMN1; SMN2POLB
SCHEMBL9441837 0.94 GAA (0.41) GAAALDH1A1LMNASMN1; SMN2TSHR
SCHEMBL8358944 0.92 GAA (0.46) GAAALDH1A1LMNASMN1; SMN2TSHR
SCHEMBL9201779 0.91 ALDH1A1 (0.46) GAAALDH1A1LMNASMN1; SMN2TSHR
SCHEMBL8354999 0.89 GAA (0.43) GAAALDH1A1LMNASMN1; SMN2TSHR
SCHEMBL10673663 0.89 GAA (0.46) GAAALDH1A1LMNASMN1; SMN2TSHR
SCHEMBL55094 0.86 GAA (0.52) GAAALDH1A1KDM4EMAPTCDK1
SCHEMBL9199246 0.85 GAA (0.49) GAAALDH1A1LMNAPOLBKDM4E
SCHEMBL8703666 0.84 FBP1 (0.41) GAAALDH1A1SMN1; SMN2POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0603240-A1 SAFENING HERBICIDAL PYRAZOLYLSULFONYLURES MONSANTO COMPANY (US) 1994-06-29 EP claimed
EP-0531271-A1 Safening herbicidal pyrazolysulfonylureas MONSANTO COMPANY (US) 1993-03-10 EP claimed
WO-1993003615-A1 SAFENING HERBICIDAL PYRAZOLYLSULFONYLURES MONSANTO COMPANY (US) 1993-03-04 WO claimed
US-4668277-A HERBICIDES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1987-05-26 US claimed
US-5880066-A COMPOSITION COMPRISING TRIAZOLOPYRIMIDINE SULFONAMIDE HERBICIDE AND OXAZOLIDINE DICHLOROACETAMIDE ANTIDOTE MONSANTO COMPANY (US) 1999-03-09 US disclosed
EP-0565593-B1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO CO (US) 1999-03-03 EP disclosed
US-5710100-A ANTIDOTES WITH HERBICIDES FOR CROPS SUCH AS CORN MONSANTO COMPANY (US) 1998-01-20 US disclosed
US-5502025-A ANTIDOTES FOR HERBICIDES AND PLANT SAFTENING AGENTS MONSANTO COMPANY (US) 1996-03-26 US disclosed
US-5484760-A AMIDES MONSANTO COMPANY (US) 1996-01-16 US disclosed
EP-0603240-A1 SAFENING HERBICIDAL PYRAZOLYLSULFONYLURES MONSANTO COMPANY (US) 1994-06-29 EP disclosed
US-5256630-A Safening mixtures of sulfonylurea and acetanilide herbicides MONSANTO COMPANY (US) 1993-10-26 US disclosed
US-5225570-A Plant safening agents for crops treated with herbicides MONSANTO COMPANY (US) 1993-07-06 US disclosed
WO-1992010098-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1992-06-25 WO disclosed
EP-0480902-A1 Safening herbicidal benzoic acid derivatives MONSANTO COMPANY (US) 1992-04-15 EP disclosed
EP-0436483-A2 Safening imidazolinone herbicides MONSANTO COMPANY (US) 1991-07-10 EP disclosed
EP-0436484-A2 Safening mixtures of sulfonylurea and acetanilide herbicides MONSANTO COMPANY (US) 1991-07-10 EP disclosed
EP-0354201-A2 Safening herbicidal benzoic acid derivatives MONSANTO COMPANY (US) 1990-02-07 EP disclosed
EP-0304409-A1 5-Heterocyclic-substituted oxazolidine haloacetamides MONSANTO COMPANY (US) 1989-02-22 EP disclosed
US-4689417-A HERBICIDE INTERMEDIATES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1987-08-25 US disclosed
US-4668277-A HERBICIDES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1987-05-26 US disclosed