Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201785 | 0.93 | KDM4E (0.48) | ALDH1A1KDM4EKDM6BKDM5CEGLN1 | |
| SCHEMBL16917389 | 0.89 | ALDH1A1 (0.60) | ALDH1A1KDM4ETSHRGAAHAO1 | |
| SCHEMBL8846311 | 0.83 | KDM4E (0.62) | ALDH1A1KDM4EKDM6BKDM5CEGLN1 | |
| SCHEMBL1421239 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4ETSHRMGAMGAA | |
| SCHEMBL24800393 | 0.81 | ALDH1A1 (0.70) | ALDH1A1TSHRHAO1RECQLLMNA | |
| SCHEMBL30432418 | 0.81 | ALDH1A1 (0.70) | ALDH1A1TSHRHAO1RECQLLMNA | |
| SCHEMBL1520914 | 0.81 | — | — | |
| SCHEMBL31549369 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KDM4ETSHRRECQLLMNA | |
| SCHEMBL11247778 | 0.81 | KDM4E (0.59) | ALDH1A1KDM4EKDM6BKDM5CEGLN1 | |
| SCHEMBL10958948 | 0.81 | KDM4E (0.59) | ALDH1A1KDM4EKDM6BKDM5CEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641329-A1 | COMPOUNDS HAVING ANGIOTENSINE II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.p.A. (IT) | 1995-03-08 | — | — | EP | disclosed |