Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMYD3 | Q9H7B4 | 6/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940011 | 0.78 | MEN1 (0.55) | MEN1KMT2ASMYD3ALDH1A1CYP3A4 | |
| SCHEMBL8940279 | 0.76 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL8939934 | 0.76 | MEN1 (0.55) | MEN1KMT2ASMYD3ALDH1A1CYP3A4 | |
| SCHEMBL13880844 | 0.74 | HTR4 (0.62) | MEN1KMT2ACYP2D6CYP2C9HTR4 | |
| SCHEMBL1559634 | 0.71 | MEN1 (0.74) | MEN1KMT2AALDH1A1CYP3A4TSHR | |
| Maleic Acid SCHEMBL9757972 | 0.71 | KDM4E (0.48) | MEN1KMT2A | |
| SCHEMBL9581804 | 0.70 | MEN1 (0.63) | MEN1KMT2ACYP2D6HTR4ALDH1A1 | |
| SCHEMBL5956281 | 0.70 | MEN1 (0.60) | MEN1KMT2ASMYD3ALDH1A1HSD17B10 | |
| SCHEMBL3540892 | 0.70 | CYP2D6 (0.62) | MEN1KMT2ACYP2D6CYP2C9HTR4 | |
| SCHEMBL1784978 | 0.70 | CYP2D6 (0.62) | MEN1KMT2ACYP2D6CYP2C9HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307172-B1 | Improvements in or relating to specific 5-HT3 antagonists | LILLY CO ELI (US) | 1995-10-11 | — | — | EP | disclosed |