SCHEMBL920182

SCHEMBL920182

Cc1cc(C)c(N2CN(c3c(C)cc(C)cc3C)C3CCCCC32)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 3/20 0.36
TAS1R1 Q7RTX1 3/20 0.36
TAS1R2 Q8TE23 3/20 0.36
UGT2B17 O75795 2/20 0.35
HRH3 Q9Y5N1 3/20 0.35
ALDH1A1 P00352 3/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
EBP Q15125 3/20 0.33
DHCR7 Q9UBM7 3/20 0.33
PSMB5 P28074 1/20 0.33
NR1I2 O75469 1/20 0.33
KDM4B O94953 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
ADRA1A P35348 1/20 0.33
DOHH Q9BU89 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819223 0.80 HRH3 (0.34) UGT2B17HRH3ALDH1A1POLBMAPT
SCHEMBL16307930 0.79 HTR2C (0.37) ALDH1A1MAPTHTTNPSR1MEN1
Hydrochloric Acid SCHEMBL819838 0.78 HRH3 (0.33) HRH3ALDH1A1POLBMAPTHTT
SCHEMBL13510558 0.78 TAS1R3 (0.38) TAS1R3TAS1R1TAS1R2UGT2B17HRH3
SCHEMBL16307937 0.75 SLC18A3 (0.41) ALDH1A1POLBMAPTHTTNPSR1
SCHEMBL13510522 0.74 UGT2B17 (0.37) TAS1R3TAS1R1TAS1R2UGT2B17HRH3
SCHEMBL920181 0.73 TAS1R3 (0.35) TAS1R3TAS1R1TAS1R2UGT2B17HRH3
SCHEMBL21562371 0.72 ALDH1A1 (0.36) HRH3ALDH1A1POLBMAPTHTT
SCHEMBL22223017 0.71 HRH3 (0.39) UGT2B17HRH3ALDH1A1POLBMAPT
SCHEMBL4552495 0.70 ALDH1A1 (0.36) TAS1R3TAS1R1TAS1R2HRH3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024085043-A1 CATALYST LIQUID AND POLYMERIZABLE COMPOSITION RIMTEC株式会社 2024-04-25 WO disclosed
WO-2024085044-A1 POLYMERIZABLE COMPOSITION AND NORBORNENE RESIN RIMTEC株式会社 2024-04-25 WO disclosed
EP-2444438-B1 POLYMERIZABLE COMPOSITION, RESIN MOLDED BODY, AND LAMINATE ZEON CORP (JP) 2020-03-18 EP disclosed
EP-2977388-B1 COPOLYMER RUBBER CONTAINING NITRILE GROUP, CROSSLINKABLE RUBBER COMPOSITION, AND RUBBER CROSSLINKED PRODUCT ZEON CORP (JP) 2019-09-04 EP disclosed
EP-2653501-B1 CROSSLINKABLE RESIN MOLDED BODY, AND LAMINATE ZEON CORP (JP) 2019-05-22 EP disclosed
US-9951247-B2 Polymerizable composition, cycloolefin-based polymer, cycloolefin-based resin molded body, and laminate ZEON CORPORATION (JP) 2018-04-24 US disclosed
US-9938253-B2 Catalysts for efficient Z-selective metathesis TRUSTEES OF BOSTON COLLEGE (US) 2018-04-10 US disclosed
EP-2960267-B1 POLYMERIZABLE COMPOSITION, CYCLOOLEFIN-BASED POLYMER, CYCLOOLEFIN-BASED RESIN MOLDED BODY, AND LAMINATE ZEON CORP (JP) 2017-08-30 EP disclosed
EP-2343340-B2 POLYMERIZABLE COMPOSITION, CROSS-LINKABLE SHAPED ARTICLE, CROSSLINKED SHAPED ARTICLE, AND CROSSLINKED SHAPED ARTICLE COMPOSITE ZEON CORP (JP) 2017-07-26 EP disclosed
US-9683067-B2 Nitrile group-containing copolymer rubber, cross-linkable rubber composition, and cross-linked rubber ZEON CORPORATION (JP) 2017-06-20 US disclosed
US-20070191563-A1 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2007-08-16 US disclosed
US-20070037946-A1 Process for producing cycloolefin resin film and process for producing cycloolefin polymer sheet or film ZEON CORPORATION (JP) 2007-02-15 US disclosed
US-7173097-B2 Metathesis-curable composition with a reaction control agent KERR CORPORATION (US) 2007-02-06 US disclosed
US-20060258828-A1 Polymerizable composition and molded articles produced by using the same ZEON CORPORATION (JP) 2006-11-16 US disclosed
US-20060211834-A1 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2006-09-21 US disclosed
US-20060154099-A1 Multilayer body and method for producing same ZEON CORPORATION (JP) 2006-07-13 US disclosed
EP-1655321-A1 POLYMERIZABLE COMPOSITIONS AND MOLDED ARTICLES PRODUCED BY USING THE SAME Zeon Corporation (JP) 2006-05-10 EP disclosed
EP-1640153-A1 MULTILAYER BODY AND METHOD FOR PRODUCING SAME Zeon Corporation (JP) 2006-03-29 EP disclosed
EP-1589055-A1 PROCESS FOR PRODUCING CYCLOOLEFIN RESIN FILM AND PROCESS FOR PRODUCING CYCLOOLEFIN POLYMER SHEET OR FILM Zeon Corporation (JP) 2005-10-26 EP disclosed
EP-1535941-A1 PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS ZEON CORPORATION (JP) 2005-06-01 EP disclosed