Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYLK | Q15746 | 5/20 | 0.72 |
| ▸ | JAK3 | P52333 | 4/20 | 0.64 |
| ▸ | KDR | P35968 | 3/20 | 0.64 |
| ▸ | PLK4 | O00444 | 1/20 | 0.64 |
| ▸ | AURKA | O14965 | 1/20 | 0.64 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.64 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.64 |
| ▸ | PAK4 | O96013 | 1/20 | 0.64 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.64 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.64 |
| ▸ | PRKCG | P05129 | 1/20 | 0.64 |
| ▸ | PRKCB | P05771 | 1/20 | 0.64 |
| ▸ | INSR | P06213 | 1/20 | 0.64 |
| ▸ | LCK | P06239 | 1/20 | 0.64 |
| ▸ | CDK1 | P06493 | 1/20 | 0.64 |
| ▸ | CSF1R | P07333 | 1/20 | 0.64 |
| ▸ | LYN | P07948 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198881 | 0.91 | MYLK (0.71) | MYLKJAK3KDRPLK4AURKA | |
| SCHEMBL9200685 | 0.88 | MYLK (0.72) | MYLKJAK3ROCK2PRKD3PRKCG | |
| SCHEMBL9199809 | 0.88 | MYLK (0.78) | MYLKROCK2PRKD3PRKCGPRKCB | |
| SCHEMBL9544956 | 0.86 | MYLK (0.78) | MYLKJAK3KDRPLK4AURKA | |
| SCHEMBL9544982 | 0.86 | MYLK (0.78) | MYLKJAK3KDRPLK4AURKA | |
| SCHEMBL9199790 | 0.86 | MYLK (0.67) | MYLKJAK3KDRPLK4AURKA | |
| SCHEMBL9544754 | 0.84 | MYLK (1.00) | MYLKJAK3KDRPLK4AURKA | |
| SCHEMBL9544964 | 0.84 | MYLK (1.00) | MYLKJAK3KDRPLK4AURKA | |
| SCHEMBL9545348 | 0.82 | MYLK (1.00) | MYLKJAK3KDRPLK4AURKA | |
| SCHEMBL9544970 | 0.82 | MYLK (1.00) | MYLKJAK3KDRPLK4AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993024490-A1 | USE OF INDOLOCARBAZOLS IN AIDS TREATMENT | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | claimed |
| US-5438050-A | Indolocarbazole derivatives, processes for their preparation and compositions containing them | GODECKE AKTIENGESELLSCHAFT (DE) | 1995-08-01 | — | — | US | disclosed |
| EP-0328000-B1 | Indolocarbazole derivatives, process for their preparation and medicines containing same | GOEDECKE AG (DE) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993024490-A1 | USE OF INDOLOCARBAZOLS IN AIDS TREATMENT | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | disclosed |
| EP-0328000-A2 | Indolocarbazole derivatives, process for their preparation and medicines containing same | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1989-08-16 | — | — | EP | disclosed |