SCHEMBL9199809

SCHEMBL9199809

CCCCCCCCCCCCCCCCCCn1c2ccccc2c2c3c(c4c5ccccc5[nH]c4c21)C(=O)NC3

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYLK Q15746 2/20 0.78
ROCK2 O75116 1/20 0.70
PRKD3 O94806 7/20 0.63
PRKCG P05129 7/20 0.63
PRKCB P05771 7/20 0.63
PRKCA P17252 7/20 0.63
PRKCH P24723 7/20 0.63
PRKCI P41743 7/20 0.63
PRKCE Q02156 7/20 0.63
PRKCQ Q04759 7/20 0.63
PRKCZ Q05513 7/20 0.63
PRKCD Q05655 7/20 0.63
PRKD1 Q15139 7/20 0.63
CDK4 P11802 2/20 0.56
CCND1 P24385 2/20 0.56
CCNE2 O96020 1/20 0.56
CCNE1 P24864 1/20 0.56
CDK2 P24941 1/20 0.56
PRKACA P17612 1/20 0.56
PRKACG P22612 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9200685 0.96 MYLK (0.72) MYLKROCK2PRKD3PRKCGPRKCB
SCHEMBL9198199 0.92 MYLK (0.77) MYLKROCK2PRKD3PRKCGPRKCB
SCHEMBL9201942 0.88 PRKD3 (0.72) MYLKROCK2PRKD3PRKCGPRKCB
SCHEMBL9195167 0.88 ROCK2 (0.74) MYLKROCK2PRKD3PRKCGPRKCB
SCHEMBL9201896 0.88 MYLK (0.72) MYLKROCK2PRKD3PRKCGPRKCB
SCHEMBL9200997 0.88 MYLK (1.00) MYLKROCK2PRKD3PRKCGPRKCB
SCHEMBL9203489 0.85 MYLK (0.73) MYLKROCK2PRKD3PRKCGPRKCB
SCHEMBL9202553 0.85 PRKD3 (0.75) MYLKROCK2PRKD3PRKCGPRKCB
SCHEMBL9203534 0.84 PRKD3 (0.71) MYLKROCK2PRKD3PRKCGPRKCB
SCHEMBL9198039 0.84 MYLK (0.93) MYLKROCK2PRKD3PRKCGPRKCB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993024490-A1 USE OF INDOLOCARBAZOLS IN AIDS TREATMENT Gödecke Aktiengesellschaft (DE) 1993-12-09 WO claimed
US-5438050-A Indolocarbazole derivatives, processes for their preparation and compositions containing them GODECKE AKTIENGESELLSCHAFT (DE) 1995-08-01 US disclosed
US-5416096-A 7-(1-pyrrolidinyl)-3-quinolone carboxylic acid derivatives as antibacterial agents and feed additives BAYER AKTIENGESELLSCHAFT (DE) 1995-05-16 US disclosed
EP-0328000-B1 Indolocarbazole derivatives, process for their preparation and medicines containing same GOEDECKE AG (DE) 1995-01-18 EP disclosed
WO-1993024490-A1 USE OF INDOLOCARBAZOLS IN AIDS TREATMENT Gödecke Aktiengesellschaft (DE) 1993-12-09 WO disclosed
US-5059597-A Animal growth regulators; enterobacter BAYER AKTIENGESELLSCHAFT (DE) 1991-10-22 US disclosed
EP-0328000-A2 Indolocarbazole derivatives, process for their preparation and medicines containing same GÖDECKE AKTIENGESELLSCHAFT (DE) 1989-08-16 EP disclosed