Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 8/20 | 0.43 |
| ▸ | NPY4R | P50391 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.41 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653899 | 0.90 | NPY1R (0.52) | TLR2NPY1RNPY4RNPY5RNPFFR1 | |
| SCHEMBL9202016 | 0.82 | NPY1R (0.62) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL8018853 | 0.78 | NPY1R (0.52) | TLR2MEN1KMT2ANPY1RNPY4R | |
| SCHEMBL9201265 | 0.78 | CTSD (0.45) | MEN1KMT2ACNR1CNR2NPY1R | |
| SCHEMBL9201253 | 0.78 | CTSD (0.45) | MEN1KMT2ACNR1CNR2NPY1R | |
| SCHEMBL27453149 | 0.76 | TLR2 (0.61) | TLR2 | |
| SCHEMBL8058943 | 0.75 | CNR1 (0.49) | MEN1KMT2ACNR1CNR2 | |
| SCHEMBL5057899 | 0.75 | NPY1R (0.53) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL1388313 | 0.75 | NPY1R (0.44) | TLR2CNR1NPY1RNPY4RNPY5R | |
| SCHEMBL9275427 | 0.74 | TLR2 (0.62) | TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |