Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA3 | P07451 | 3/20 | 0.46 |
| ▸ | CA6 | P23280 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CUL4A | Q13619 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798234 | 0.87 | CA12 (0.46) | CA12CA2CA3CA6CA7 | |
| SCHEMBL2323034 | 0.84 | ALDH1A1 (0.50) | CA12CA2CA3CA6CA7 | |
| Hydrochloric Acid SCHEMBL9797800 | 0.84 | CA12 (0.44) | CA12CA2CA3CA6CA7 | |
| SCHEMBL9204717 | 0.83 | MAOB (0.46) | CA12CA2CA3CA6CA7 | |
| SCHEMBL6545797 | 0.82 | MAOB (0.58) | CA12CA2CA3CA6CA7 | |
| SCHEMBL4683562 | 0.81 | FLT3 (0.49) | CA12CA2CA3CA6CA7 | |
| SCHEMBL6545788 | 0.80 | MAOB (0.60) | CA12CA2CA3CA6CA7 | |
| SCHEMBL1066544 | 0.80 | CA12 (0.55) | CA12CA2CA3CA6CA7 | |
| SCHEMBL6021921 | 0.77 | CA12 (0.50) | CA12CA2CA9KMT2AMAOB | |
| SCHEMBL9797830 | 0.74 | CUL4A (0.39) | CA12CA2CA3CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450566-B1 | Substituted azoles, method for their preparation, these containing compositions and their use | HOECHST AG (DE) | 1995-07-05 | — | — | EP | disclosed |
| EP-0450566-A1 | Substituted azoles, method for their preparation, these containing compositions and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |