Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | FOS | P01100 | 2/20 | 0.45 |
| ▸ | JUN | P05412 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 2/20 | 0.41 |
| ▸ | MAX | P61244 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084680 | 0.86 | MAPT (0.44) | ALDH1A1PDE4BHIF1ATSHRMAPT | |
| SCHEMBL9662252 | 0.85 | ALDH1A1 (0.65) | ALDH1A1GAAPDE4BHIF1AFOS | |
| SCHEMBL4277079 | 0.82 | HTT (0.54) | ALDH1A1GAAPDE4BHIF1AFOS | |
| SCHEMBL4717489 | 0.81 | PDK1 (0.52) | HIF1AXDHMYCMAXEP300 | |
| SCHEMBL184107 | 0.81 | TSHR (0.60) | ALDH1A1TSHR | |
| SCHEMBL24211441 | 0.78 | TSHR (0.40) | HTTTSHRMAPT | |
| SCHEMBL10761483 | 0.78 | ALDH1A1 (0.60) | ALDH1A1PDE4BHIF1AHTTTSHR | |
| SCHEMBL17908022 | 0.78 | TSHR (0.69) | PDE4BHTTTSHRDHODH | |
| SCHEMBL4275354 | 0.78 | CA12 (0.67) | PDE4BHTTTSHRMYCMAX | |
| SCHEMBL6584657 | 0.78 | ALDH1A1 (0.60) | ALDH1A1PDE4BHIF1AHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304155-B1 | Cephalosporin compounds, process for their preparation and their pharmaceutical compositions | ZENECA PHARMA SA (FR) | 1995-11-15 | — | — | EP | disclosed |
| US-5013730-A | Antibiotics | ICI-PHARMA (FR) | 1991-05-07 | — | — | US | disclosed |