Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002160 | 0.86 | KMT2A (0.56) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL28953620 | 0.86 | HSD17B10 (0.60) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL29935483 | 0.86 | HSD17B10 (0.60) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL8223617 | 0.83 | FKBP1A (0.58) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL1401256 | 0.83 | FKBP1A (0.58) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL440340 | 0.83 | FKBP1A (0.58) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL20626011 | 0.83 | MEN1 (0.50) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL28916508 | 0.82 | KMT2A (0.55) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL28581241 | 0.82 | KMT2A (0.55) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL28915732 | 0.82 | KMT2A (0.55) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210883-B1 | Derivatives of penem | DAIICHI SEIYAKU CO (JP) | 1995-02-01 | — | — | EP | disclosed |
| US-5079357-A | Bactericides | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| US-4962202-A | PENICILLIN INTERMEDIATES | DAIICHI SEIYAKU CO., LTD. (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0210883-A2 | Derivatives of penem | DAIICHI SEIYAKU CO., LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |