Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3229386 | 0.83 | SLC6A2 (0.43) | SLC6A4P2RX7CYP2C19PARP1SLC6A2 | |
| SCHEMBL3226894 | 0.80 | SLC6A2 (0.66) | SLC6A4P2RX7SLC6A2HTR2AMTNR1A | |
| SCHEMBL9206196 | 0.80 | CYP2C19 (0.40) | SLC6A4P2RX7CYP2C19PARP1SLC6A2 | |
| SCHEMBL2586507 | 0.80 | P2RX7 (0.50) | P2RX7CYP2C19PARP1CDC7CDK2 | |
| SCHEMBL4087126 | 0.73 | SLC6A4 (0.49) | SLC6A4P2RX7CYP2C19PARP1SLC6A2 | |
| SCHEMBL9266746 | 0.73 | PARP1 (0.39) | SLC6A4P2RX7CYP2C19PARP1SLC6A2 | |
| SCHEMBL8135638 | 0.71 | PARP1 (0.47) | CYP2C19PARP1CDC7CDK2HTR2A | |
| SCHEMBL23938013 | 0.71 | PARP1 (0.46) | CYP2C19PARP1CDC7CDK2ENPP1 | |
| SCHEMBL598048 | 0.71 | PARP1 (0.46) | CYP2C19PARP1CDC7CDK2ENPP1 | |
| SCHEMBL30991276 | 0.71 | PARP1 (0.46) | CYP2C19PARP1CDC7CDK2ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557171-B1 | Azaindoles, process for their preparation and medicines containing them | LIPHA (FR) | 1995-07-19 | — | — | EP | disclosed |
| US-5338849-A | Treating hyperlipidemia, atherosclerosis | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1994-08-16 | — | — | US | disclosed |
| EP-0557171-A1 | Azaindoles, process for their preparation and medicines containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1993-08-25 | — | — | EP | disclosed |