Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203069 | 0.80 | SLC6A4 (0.43) | CYP2C19P2RX7PARP1SLC22A12KDM4E | |
| SCHEMBL3229386 | 0.77 | SLC6A2 (0.43) | CYP2C19P2RX7PARP1SLC22A12KDM4E | |
| SCHEMBL3226894 | 0.74 | SLC6A2 (0.66) | P2RX7SLC6A2SLC6A4MTNR1A | |
| SCHEMBL2586507 | 0.74 | P2RX7 (0.50) | CYP2C19P2RX7PARP1SLC22A12KDM4E | |
| SCHEMBL27984061 | 0.70 | NPC1 (0.41) | CNR1NPC1ADAM17KDM4EMAPT | |
| SCHEMBL4087126 | 0.68 | SLC6A4 (0.49) | CYP2C19P2RX7PARP1SLC6A2SLC6A4 | |
| SCHEMBL9266746 | 0.68 | PARP1 (0.39) | CYP2C19P2RX7PARP1SLC22A12MAPT | |
| SCHEMBL28041794 | 0.68 | ALDH1A1 (0.48) | CNR1KDM4EMAPTPKMALDH1A1 | |
| SCHEMBL20181945 | 0.67 | PARP1 (0.41) | CYP2C19P2RX7PARP1SLC22A12SLC6A2 | |
| SCHEMBL28137577 | 0.67 | CNR1 (0.43) | CNR1KDM4EMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557171-B1 | Azaindoles, process for their preparation and medicines containing them | LIPHA (FR) | 1995-07-19 | — | — | EP | disclosed |
| US-5338849-A | Treating hyperlipidemia, atherosclerosis | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1994-08-16 | — | — | US | disclosed |
| EP-0557171-A1 | Azaindoles, process for their preparation and medicines containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1993-08-25 | — | — | EP | disclosed |