Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 4/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.46 |
| ▸ | CHRNG | P07510 | 3/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.46 |
| ▸ | CHRND | Q07001 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203101 | 1.00 | GRIA1 (0.46) | GRIA1CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL9203776 | 0.87 | MMP2 (0.54) | GRIA1CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL9203767 | 0.87 | MMP2 (0.54) | GRIA1CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL9277064 | 0.84 | HTT (0.52) | MMP2CA2NPC1LMNA | |
| SCHEMBL9277060 | 0.84 | HTT (0.52) | MMP2CA2NPC1LMNA | |
| SCHEMBL9276580 | 0.80 | MC4R (0.48) | MMP2 | |
| SCHEMBL9276586 | 0.80 | MC4R (0.48) | MMP2 | |
| SCHEMBL8365151 | 0.77 | HDAC8 (0.53) | MMP2 | |
| SCHEMBL8365152 | 0.77 | HDAC8 (0.53) | MMP2 | |
| SCHEMBL8365150 | 0.77 | HDAC8 (0.53) | MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |