Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.44 |
| ▸ | CHRNG | P07510 | 4/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.44 |
| ▸ | CHRND | Q07001 | 4/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203776 | 1.00 | MMP2 (0.54) | MMP2LTA4HGRIN1GRIN2AMEN1 | |
| SCHEMBL9203101 | 0.87 | GRIA1 (0.46) | MMP2LTA4HCHRNA1CHRNGCHRNB1 | |
| SCHEMBL9203087 | 0.87 | GRIA1 (0.46) | MMP2LTA4HCHRNA1CHRNGCHRNB1 | |
| SCHEMBL9276586 | 0.84 | MC4R (0.48) | MMP2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL9276580 | 0.84 | MC4R (0.48) | MMP2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL9277064 | 0.82 | HTT (0.52) | MMP2KMT2ACNR2 | |
| SCHEMBL9277060 | 0.82 | HTT (0.52) | MMP2KMT2ACNR2 | |
| SCHEMBL3956760 | 0.81 | ALPI (0.58) | MMP2LTA4HMEN1KMT2AHDAC8 | |
| SCHEMBL6253114 | 0.81 | ALPI (0.58) | MMP2LTA4HMEN1KMT2AHDAC8 | |
| SCHEMBL6864434 | 0.81 | HPGD (0.46) | MMP2GRIN1GRIN2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |