Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 4/20 | 0.37 |
| ▸ | MC5R | P33032 | 3/20 | 0.32 |
| ▸ | MC3R | P41968 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203124 | 1.00 | MC4R (0.37) | MC4RMC5RMC3RMMP2NOS1 | |
| SCHEMBL9195613 | 0.91 | MC4R (0.37) | MC4RMC5RMC3RMMP2NOS1 | |
| SCHEMBL9195595 | 0.91 | MC4R (0.37) | MC4RMC5RMC3RMMP2NOS1 | |
| SCHEMBL9199883 | 0.90 | MC4R (0.37) | MC4RMC5RMC3RMMP2NOS1 | |
| SCHEMBL9200382 | 0.88 | MC4R (0.38) | MC4RMC5RMC3R | |
| SCHEMBL9197220 | 0.88 | MC4R (0.38) | MC4RMC5RMC3R | |
| SCHEMBL9199354 | 0.86 | ALDH1A1 (0.37) | MC4R | |
| SCHEMBL9287552 | 0.80 | TAAR1 (0.36) | MC4R | |
| SCHEMBL9287538 | 0.80 | TAAR1 (0.36) | MC4R | |
| SCHEMBL9203109 | 0.79 | MC4R (0.32) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |