Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 3/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 2/20 | 0.31 |
| ▸ | MC3R | P41968 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203124 | 0.90 | MC4R (0.37) | MC4RMC5RMC3RMMP2NOS1 | |
| SCHEMBL9195595 | 0.90 | MC4R (0.37) | MC4RMC5RMC3RMMP2NOS1 | |
| SCHEMBL9195613 | 0.90 | MC4R (0.37) | MC4RMC5RMC3RMMP2NOS1 | |
| SCHEMBL9203091 | 0.90 | MC4R (0.37) | MC4RMC5RMC3RMMP2NOS1 | |
| SCHEMBL9197220 | 0.87 | MC4R (0.38) | MC4RKMT2AMC5RMC3R | |
| SCHEMBL9200382 | 0.87 | MC4R (0.38) | MC4RKMT2AMC5RMC3R | |
| SCHEMBL9199354 | 0.85 | ALDH1A1 (0.37) | MC4RALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9199892 | 0.79 | NR1D1 (0.36) | MC4RNR1D1DPP7ALDH1A1HTT | |
| SCHEMBL9287552 | 0.79 | TAAR1 (0.36) | MC4RALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL9287538 | 0.79 | TAAR1 (0.36) | MC4RALDH1A1HTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |