Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 4/20 | 0.45 |
| ▸ | MC5R | P33032 | 3/20 | 0.45 |
| ▸ | MC3R | P41968 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388851 | 0.90 | SLC7A5 (0.43) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL9200732 | 0.86 | DPP7 (0.41) | SLC7A5MC4RMC5RMC3RTDP1 | |
| SCHEMBL9198257 | 0.84 | TDP1 (0.49) | SLC7A5TDP1MEN1KMT2AOPRD1 | |
| SCHEMBL9198245 | 0.84 | TDP1 (0.49) | SLC7A5TDP1MEN1KMT2AOPRD1 | |
| SCHEMBL9195704 | 0.82 | ALDH1A1 (0.39) | MC4RTDP1MEN1KMT2A | |
| SCHEMBL9203137 | 0.80 | TDP1 (0.46) | TDP1MEN1KMT2A | |
| SCHEMBL9196505 | 0.80 | TDP1 (0.50) | SLC7A5TDP1MEN1KMT2A | |
| SCHEMBL8119790 | 0.76 | EPHX1 (0.44) | SLC7A5TDP1MEN1KMT2AOPRD1 | |
| SCHEMBL4156779 | 0.75 | OPRM1 (0.53) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL29053326 | 0.74 | SLC7A5 (0.50) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |