Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203177 | 0.92 | POLB (0.55) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9201311 | 0.88 | RXFP1 (0.59) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9200001 | 0.88 | KMT2A (0.53) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9205774 | 0.86 | RAB9A (0.53) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9201027 | 0.84 | KDM4E (0.59) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7640498 | 0.83 | CA12 (0.51) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9202732 | 0.83 | CA12 (0.51) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9208681 | 0.82 | CA12 (0.50) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9203805 | 0.82 | L3MBTL1 (0.54) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9527322 | 0.81 | MEN1 (0.42) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550493-B1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | UPJOHN CO (US) | 1995-08-09 | — | — | EP | claimed |
| EP-0550493-A1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1993-07-14 | — | — | EP | claimed |
| WO-1992006083-A1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-04-16 | — | — | WO | claimed |