Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CAD | P27708 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213373 | 0.87 | CYP2C19 (0.40) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL1415615 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL22144315 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL235849 | 0.83 | ALDH1A1 (0.50) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL10867163 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL11302245 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL3464999 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 | |
| SCHEMBL30438662 | 0.77 | ZDHHC7 (0.42) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL9205071 | 0.77 | ZDHHC7 (0.42) | ALDH1A1TRPA1MGAMGAASI | |
| SCHEMBL23255902 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TRPA1LMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643710-A1 | SYNTHESIS OF OPTICALLY ACTIVE LACTONES FROM L-ASPARTIC ACID AND INTERMEDIATES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5322942-A | Deprotecting and hydrolyzing protected aspartic acid diester, reacting with nitrosylating agent in presence of hydrogen halide, esterifying, reacting with acyl aryl derivative | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-06-21 | — | — | US | disclosed |
| WO-1992021675-A1 | SYNTHESIS OF OPTICALLY ACTIVE LACTONES FROM L-ASPARTIC ACID AND INTERMEDIATES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-12-10 | — | — | WO | disclosed |