Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16322756 | 0.86 | PRSS1 (0.39) | BRD4MEN1KMT2ACREBBPTP53 | |
| SCHEMBL9201147 | 0.86 | MAPT (0.43) | KDM4EBRD4MEN1KMT2AMAPT | |
| SCHEMBL9142318 | 0.86 | LMNA (0.46) | HSD17B10 | |
| Hydrochloric Acid SCHEMBL9208972 | 0.85 | PRSS1 (0.38) | BRD4MEN1KMT2ACREBBPTP53 | |
| SCHEMBL17275862 | 0.84 | MYC (0.44) | KDM4EALDH1A1SMN1; SMN2MAPTTP53 | |
| Hydrochloric Acid SCHEMBL17275789 | 0.82 | CBX7 (0.40) | BRD4ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL16324200 | 0.82 | CASP3 (0.50) | KDM4EALDH1A1HSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL30035463 | 0.82 | CASP3 (0.50) | KDM4EALDH1A1HSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL9205679 | 0.81 | CBX7 (0.41) | BRD4ALDH1A1MAPTCREBBPTSHR | |
| SCHEMBL18549359 | 0.79 | MAPK14 (0.40) | KDM4EBRD4ALDH1A1HSD17B10BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497852-B1 | BICYCLO-IMIDAZOLES, PROCESS FOR PRODUCING THEM AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1991006545-A1 | BICYCLO-IMIDAZOLES, PROCESS FOR PRODUCING THEM AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1991-05-16 | — | — | WO | disclosed |