Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9215684 | 0.99 | ADORA3 (0.39) | ADORA3TSHRNPSR1LMNATP53 | |
| Hydrochloric Acid SCHEMBL9216313 | 0.99 | ADORA3 (0.39) | ADORA3TSHRNPSR1LMNATP53 | |
| Hydrochloric Acid SCHEMBL9212238 | 0.98 | ADORA3 (0.40) | ADORA3TSHRNPSR1LMNATP53 | |
| Hydrochloric Acid SCHEMBL9205116 | 0.96 | ADORA3 (0.40) | ADORA3TSHRNPSR1LMNATP53 | |
| Hydrochloric Acid SCHEMBL9203780 | 0.94 | ADORA3 (0.41) | ADORA3TSHRNPSR1LMNATP53 | |
| Hydrochloric Acid SCHEMBL9337436 | 0.88 | ALDH1A1 (0.38) | TSHRNPSR1LMNATP53KDM4E | |
| Hydrochloric Acid SCHEMBL9212528 | 0.88 | ALDH1A1 (0.38) | TSHRNPSR1LMNATP53KDM4E | |
| Hydrochloric Acid SCHEMBL9205123 | 0.86 | KDM4E (0.39) | TSHRNPSR1LMNATP53KDM4E | |
| Hydrochloric Acid SCHEMBL9208080 | 0.84 | KDM4E (0.39) | TSHRNPSR1LMNATP53KDM4E | |
| Hydrochloric Acid SCHEMBL9212505 | 0.83 | NPSR1 (0.53) | TSHRNPSR1MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536169-B1 | [3H,7H]THIAZOLO [3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA (IT) | 1995-04-05 | — | — | EP | disclosed |
| US-5336676-A | [3H,7H]thiazolo[3,4-a]pyridines with antiasthmatic and antiinflammatory actions on the respiratory tract | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1994-08-09 | — | — | US | disclosed |
| EP-0536169-A1 | 3H,7H]THIAZOLO 3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT. | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-04-14 | — | — | EP | disclosed |
| WO-1991018906-A1 | [3H,7H]THIAZOLO[3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-12-12 | — | — | WO | disclosed |