Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17596778 | 0.74 | HSD17B10 (0.48) | ALDH1A1HSD17B10RECQLCA12CA1 | |
| SCHEMBL27805323 | 0.74 | HSD17B10 (0.48) | ALDH1A1HSD17B10RECQLCA12CA1 | |
| SCHEMBL9220984 | 0.74 | LOXL2 (0.42) | ALDH1A1HSD17B10RECQLCA12CA1 | |
| SCHEMBL9211149 | 0.72 | NPC1 (0.46) | ALDH1A1RECQLMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL2082451 | 0.69 | HSD17B10 (0.47) | ALDH1A1HSD17B10RECQLMAPTSMN1; SMN2 | |
| SCHEMBL29177330 | 0.69 | HSD17B10 (0.47) | ALDH1A1HSD17B10RECQLMAPTSMN1; SMN2 | |
| SCHEMBL10969691 | 0.68 | MAPK1 (0.45) | ALDH1A1MAPTSMN1; SMN2MAPK1HTR1E | |
| SCHEMBL2083556 | 0.67 | HSD17B10 (0.44) | ALDH1A1HSD17B10RECQLMAPTACHE | |
| SCHEMBL9812380 | 0.66 | HSD17B10 (0.52) | ALDH1A1HSD17B10RECQLCA12CA1 | |
| SCHEMBL20312474 | 0.66 | HSD17B10 (0.42) | ALDH1A1HSD17B10RECQLCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662969-A1 | UREA AND THIOUREA DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA & UPJOHN S.p.A. (IT) | 1995-07-19 | — | — | EP | disclosed |