Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206180 | 0.87 | ALOX5 (0.38) | ALOX5 | |
| SCHEMBL8556574 | 0.82 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9087090 | 0.82 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9208296 | 0.77 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL8556671 | 0.76 | MAP2K1 (0.32) | — | |
| SCHEMBL9085038 | 0.71 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL9086267 | 0.71 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL9086220 | 0.68 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9206036 | 0.67 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL9086529 | 0.66 | SLC6A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462812-B1 | Pyran derivatives as inhibitors of 5-lipoxygenase | ZENECA LTD (GB) | 1995-12-06 | — | — | EP | claimed |