Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENO1 | P06733 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 4/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | MMP8 | P22894 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL11182752 | 0.94 | CA2 (0.47) | ENO1CA2CA4MMP1MMP2 | |
| SCHEMBL13024165 | 0.84 | MMP1 (0.48) | ENO1CA2CA4MMP1MMP2 | |
| SCHEMBL5058464 | 0.80 | CA2 (0.56) | ENO1CA2CA4MEN1KMT2A | |
| SCHEMBL11692175 | 0.74 | MMP1 (0.43) | ENO1CA2MMP1MMP2MMP8 | |
| SCHEMBL13024162 | 0.74 | MMP1 (0.43) | ENO1CA2MMP1MMP2MMP8 | |
| SCHEMBL5909175 | 0.73 | MEN1 (0.52) | CA2MMP1MMP2MMP8CA12 | |
| SCHEMBL6234582 | 0.73 | MMP1 (0.57) | ENO1CA2CA4MMP1MMP8 | |
| SCHEMBL2329365 | 0.73 | TSHR (0.41) | CA2MMP1MMP2MMP8CA12 | |
| SCHEMBL7482527 | 0.72 | — | — | |
| SCHEMBL3313335 | 0.71 | MEN1 (0.50) | CA2MMP1MMP2MMP8CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102770139-B | Compound based on Sanglifehrin | BIOTICA TECHNOLOGY LTD. (SE) | 2016-11-30 | — | — | CN | disclosed |
| CN-102770139-A | Sanglifehrin based compounds | BIOTICA TECH LTD | 2012-11-07 | — | — | CN | disclosed |
| EP-0411664-B1 | 2-(2-Vinylpyrrolidinylthio)carbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1995-01-18 | — | — | EP | disclosed |
| US-5095013-A | Antibiotics | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-03-10 | — | — | US | disclosed |
| EP-0411664-A2 | 2-(2-Vinylpyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-02-06 | — | — | EP | disclosed |