Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207424 | 1.00 | SHBG (0.34) | SHBGSIGMAR1TSHREPHX1EPHX2 | |
| SCHEMBL9209181 | 0.98 | SHBG (0.38) | SHBGSIGMAR1TSHREPHX1EPHX2 | |
| SCHEMBL10472499 | 0.98 | SHBG (0.38) | SHBGSIGMAR1TSHREPHX1EPHX2 | |
| SCHEMBL9210781 | 0.98 | SHBG (0.38) | SHBGSIGMAR1TSHREPHX1EPHX2 | |
| SCHEMBL108105 | 0.98 | SHBG (0.35) | SHBGSIGMAR1TSHREPHX1 | |
| SCHEMBL1524594 | 0.96 | SHBG (0.39) | SHBGSIGMAR1TSHREPHX1EPHX2 | |
| SCHEMBL9205067 | 0.92 | SHBG (0.37) | SHBGSIGMAR1 | |
| SCHEMBL1524470 | 0.92 | LMNA (0.35) | TSHR | |
| SCHEMBL28859417 | 0.88 | SHBG (0.39) | SHBGSIGMAR1TSHREPHX1 | |
| SCHEMBL29322013 | 0.88 | SHBG (0.39) | SHBGSIGMAR1TSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |