SCHEMBL920451

SCHEMBL920451

[C]1N(C2CCCCC2)CCCN1C1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
PHGDH O43175 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920706 0.92 MEN1 (0.32) KMT2AMEN1PHGDHMGLL
SCHEMBL9059294 0.74
SCHEMBL28901686 0.67 PHGDH (0.48) KMT2AMEN1PHGDHMGLL
SCHEMBL9363970 0.67 PHGDH (0.48) KMT2AMEN1PHGDHMGLL
SCHEMBL2635230 0.67 PHGDH (0.48) KMT2AMEN1PHGDHMGLL
SCHEMBL9044554 0.65
SCHEMBL8789877 0.65
SCHEMBL8788678 0.65
SCHEMBL5246612 0.65 HTR6 (0.33)
SCHEMBL12856247 0.65 PHGDH (0.52) KMT2AMEN1ALDH1A1PHGDHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2444438-B1 POLYMERIZABLE COMPOSITION, RESIN MOLDED BODY, AND LAMINATE ZEON CORP (JP) 2020-03-18 EP disclosed
EP-2977388-B1 COPOLYMER RUBBER CONTAINING NITRILE GROUP, CROSSLINKABLE RUBBER COMPOSITION, AND RUBBER CROSSLINKED PRODUCT ZEON CORP (JP) 2019-09-04 EP disclosed
EP-2653501-B1 CROSSLINKABLE RESIN MOLDED BODY, AND LAMINATE ZEON CORP (JP) 2019-05-22 EP disclosed
US-20180127520-A1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION ZEON CORPORATION (JP) 2018-05-10 US disclosed
US-9683067-B2 Nitrile group-containing copolymer rubber, cross-linkable rubber composition, and cross-linked rubber ZEON CORPORATION (JP) 2017-06-20 US disclosed
US-9650462-B2 Polymerizable composition, resin shaped article, and laminate ZEON CORPORATION (JP) 2017-05-16 US disclosed
US-20160289372-A1 POLYMERIZABLE COMPOSITION, RESIN SHAPED ARTICLE, COMPOSITE, AND LAMINATE ZEON CORPORATION (JP) 2016-10-06 US disclosed
US-20160122457-A1 NITRILE GROUP-CONTAINING COPOLYMER RUBBER, CROSS-LINKABLE RUBBER COMPOSITION, AND CROSS-LINKED RUBBER ZEON CORPORATION (JP) 2016-05-05 US disclosed
EP-2620483-B1 ADHESIVE FILM FOR ORGANIC ELECTROLYTE ACCUMULATOR DEVICES ZEON CORP (JP) 2016-02-10 EP disclosed
EP-2977388-A1 COPOLYMER RUBBER CONTAINING NITRILE GROUP, CROSSLINKABLE RUBBER COMPOSITION, AND RUBBER CROSSLINKED PRODUCT Zeon Corporation (JP) 2016-01-27 EP disclosed
US-7084222-B2 Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst ZEON CORPORATION (JP) 2006-08-01 US disclosed
US-20060154099-A1 Multilayer body and method for producing same ZEON CORPORATION (JP) 2006-07-13 US disclosed
EP-1640153-A1 MULTILAYER BODY AND METHOD FOR PRODUCING SAME Zeon Corporation (JP) 2006-03-29 EP disclosed
EP-1275675-B1 COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE ZEON CORP (JP) 2005-12-07 EP disclosed
EP-1589055-A1 PROCESS FOR PRODUCING CYCLOOLEFIN RESIN FILM AND PROCESS FOR PRODUCING CYCLOOLEFIN POLYMER SHEET OR FILM Zeon Corporation (JP) 2005-10-26 EP disclosed
EP-1535941-A1 PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS ZEON CORPORATION (JP) 2005-06-01 EP disclosed
US-20050014916-A1 Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst ZEON CORPORATION (JP) 2005-01-20 US disclosed
US-6815516-B2 HEAT RESISTANCE, SOLVENT SOLUBILITY ZEON CORPORATION (JP) 2004-11-09 US disclosed
US-20030018138-A1 Copolymer formed by ring -opening polymerization, product of hydrogenation of copolymer formed by ring-opening polymerization, and process for producing these ZEON CORPORATION (JP) 2003-01-23 US disclosed
EP-1275675-A1 COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE Zeon Corporation (JP) 2003-01-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014916-A1 Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst POR, CAD, HRH1 KMT2A 1706/4885MEN1 2549/4885ALDH1A1 3138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.