Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211183 | 0.98 | LMNA (0.50) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL5142110 | 0.98 | LMNA (0.50) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL9205053 | 0.98 | LMNA (0.50) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL1873149 | 0.92 | ALDH1A1 (0.54) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL17135388 | 0.90 | LMNA (0.50) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL29155842 | 0.89 | ALDH1A1 (0.43) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL20821296 | 0.87 | LMNA (0.54) | LMNATSHROPRM1CA1SPHK1 | |
| SCHEMBL22471932 | 0.87 | LMNA (0.54) | LMNATSHROPRM1CA1SPHK1 | |
| SCHEMBL29640413 | 0.87 | LMNA (0.54) | LMNATSHROPRM1CA1SPHK1 | |
| SCHEMBL5683598 | 0.87 | LMNA (0.54) | LMNATSHROPRM1CA1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |