Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 6/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3730455 | 0.86 | LMNA (0.62) | LMNAHSD17B10SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL21914 | 0.79 | HTT (0.62) | LMNAHSD17B10SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL29380490 | 0.79 | HTT (0.62) | LMNAHSD17B10SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL16145699 | 0.78 | HTT (0.65) | LMNAHSD17B10SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL6243538 | 0.78 | HTT (0.60) | LMNAHSD17B10SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL10918760 | 0.78 | HTT (0.60) | LMNAHSD17B10SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL25176526 | 0.78 | SMN1; SMN2 (0.54) | LMNAHSD17B10SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL11591794 | 0.77 | HTT (0.59) | LMNAHSD17B10SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL31095854 | 0.77 | CYP1A2 (0.57) | LMNAHSD17B10SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL405823 | 0.76 | HTT (0.58) | LMNAHSD17B10SMN1; SMN2HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155418-A9 | MODIFIED OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| WO-2023028350-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |
| EP-0286425-B1 | Therapeutic nucleosides | WELLCOME FOUND (GB) | 1995-01-11 | — | — | EP | disclosed |
| US-5185437-A | 6-substituted 2',3'-dideoxypurine nucleosides; treatment for human immunodeficiency virus and heptatis b virus | BURROUGHS WELLCOME CO. (US) | 1993-02-09 | — | — | US | disclosed |
| US-5068320-A | 2-amino-6-(cyclopropylamino)purine-9-β-D-2',3'-dideoxyribofuranoside and its pharmaceutically acceptable salts | BURROUGHS WELLCOME CO. (US) | 1991-11-26 | — | — | US | disclosed |
| US-4849423-A | Purine derivatives, medicaments containing them and methods of treating cardiac insufficiencies and irregularities with them. | SANDOZ LTD. (CH) | 1989-07-18 | — | — | US | disclosed |
| EP-0286425-A2 | Therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-10-12 | — | — | EP | disclosed |