SCHEMBL21914

SCHEMBL21914

CNc1ncnc2nc[nH]c12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 6/20 0.62
CYP1A2 P05177 3/20 0.60
HIF1A Q16665 1/20 0.60
CYP3A4 P08684 1/20 0.57
LMNA P02545 7/20 0.57
XDH P47989 2/20 0.56
PAK1 Q13153 1/20 0.56
CDK2 P24941 2/20 0.55
HSD17B10 Q99714 4/20 0.54
PKM P14618 1/20 0.54
MKNK1 Q9BUB5 1/20 0.54
RAB9A P51151 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
NPC1 O15118 1/20 0.54
PRMT1 Q99873 1/20 0.54
TSHR P16473 2/20 0.53
MAPK1 P28482 2/20 0.53
CYP2D6 P10635 1/20 0.53
GFER P55789 1/20 0.53
DRD3 P35462 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29380490 1.00 HTT (0.62) HTTCYP1A2HIF1ACYP3A4LMNA
SCHEMBL10918760 0.98 HTT (0.60) HTTCYP1A2HIF1ACYP3A4LMNA
SCHEMBL6243538 0.98 HTT (0.60) HTTCYP1A2HIF1ACYP3A4LMNA
Trimethylammonium SCHEMBL27585897 0.94 HTT (0.57) HTTCYP1A2HIF1ACYP3A4LMNA
Adenine SCHEMBL29242838 0.90 LMNA (0.71) HTTCYP1A2HIF1ACYP3A4LMNA
SCHEMBL405823 0.85 HTT (0.58) HTTCYP1A2HIF1ACYP3A4LMNA
SCHEMBL5628458 0.82 HTT (0.63) HTTCYP1A2CYP3A4LMNACDK2
SCHEMBL11591794 0.82 HTT (0.59) HTTCYP1A2HIF1ACYP3A4LMNA
SCHEMBL160074 0.80 CYP3A4 (0.62) HTTCYP1A2HIF1ACYP3A4LMNA
SCHEMBL17901710 0.80 HTT (0.57) HTTCYP1A2HIF1ACYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11825 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
WO-2026107204-A1 METHODS FOR ANALYZING LOW-DEPTH GENOME SEQUENCING DATA TO DETECT MINIMAL RESIDUAL DISEASE GUARDANT HEALTH, INC. (US) 2026-05-21 WO claimed
CN-122038534-A Construction method of DNA library with modified nucleotide and application thereof 深圳华大智造科技股份有限公司 2026-05-15 CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
EP-4735634-A1 SYSTEMS AND METHODS OF SEQUENCING POLYNUCLEOTIDES WITH MODIFIED BASES Illumina, Inc. (US) 2026-05-06 EP claimed
WO-2026088246-A1 METHOD FOR PRODUCING LOW-MOLECULAR-WEIGHT COMPOUND NTT株式会社 2026-04-30 WO claimed
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION TRILINK BIOTECHNOLOGIES, LLC (US) 2026-04-23 US claimed
US-20260098287-A1 METHOD AND KIT FOR REGENERATING REUSABLE INITIATORS FOR NUCLEIC ACID SYNTHESIS CHENG-YAO CHEN (TW) 2026-04-09 US claimed
CN-1100728-A Nucleosides and oligonucleotides having 2'-ether groups CIBA GEIGY AG (CH) 1995-03-29 CN claimed
US-5332814-A Process for the preparation of carbacyclic nucleosides, and intermediates CIBA-GEIGY CORPORATION (US) 1994-07-26 US claimed
US-5319080-A Antiviral agents CIBA-GEIGY CORPORATION (US) 1994-06-07 US claimed
EP-0540686-A4 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1993-05-26 EP claimed
EP-0540686-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES. US COMMERCE (US) 1993-05-12 EP claimed
EP-0525106-A4 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS 1993-04-21 EP claimed
EP-0525106-A1 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS SOUTHERN RESEARCH INSTITUTE (US) 1993-02-03 EP claimed
US-5183732-A Adenine-type grain growth modifier EASTMAN KODAK COMPANY (US) 1993-02-02 US claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed
CN-1036578-A NOVEL FLUOROPHOSPHONATE NUCLEOTIDE DERIVATIVES MERRELL DOW PHARMA (US) 1989-10-25 CN claimed