Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888873 | 0.98 | ALDH1A1 (0.60) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL9204714 | 0.86 | ALDH1A1 (0.59) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL3091610 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL9204606 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL15014082 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL25218201 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL3300574 | 0.80 | L3MBTL1 (0.58) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL7311249 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL8888879 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 | |
| SCHEMBL13181154 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTTP53TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489877-B1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES | UPJOHN CO (US) | 1995-09-20 | — | — | EP | disclosed |