Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820709 | 0.81 | EPHX1 (0.57) | EPHX1HPGDL3MBTL1KDM4EKMT2A | |
| SCHEMBL968277 | 0.77 | NPC1 (0.36) | EPHX1HPGDKDM4EKMT2AALDH1A1 | |
| SCHEMBL17975428 | 0.75 | EPHX1 (0.52) | EPHX1HPGDL3MBTL1KDM4EKMT2A | |
| SCHEMBL16890324 | 0.75 | EPHX1 (0.52) | EPHX1HPGDL3MBTL1KDM4EKMT2A | |
| SCHEMBL10071176 | 0.73 | EPHX1 (0.60) | EPHX1HPGDL3MBTL1KDM4EKMT2A | |
| SCHEMBL11800970 | 0.73 | EPHX1 (0.50) | EPHX1HPGDL3MBTL1KDM4EKMT2A | |
| SCHEMBL968781 | 0.72 | — | — | |
| SCHEMBL6338852 | 0.72 | — | — | |
| SCHEMBL2625566 | 0.71 | EPHX1 (0.48) | EPHX1HPGDL3MBTL1KDM4EKMT2A | |
| SCHEMBL17975431 | 0.71 | ALDH1A1 (0.55) | EPHX1HPGDL3MBTL1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637298-A1 | SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM | BASF Aktiengesellschaft (DE) | 1995-02-08 | — | — | EP | disclosed |