Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820709 | 0.85 | EPHX1 (0.57) | EPHX1KDM4CHPGDL3MBTL1KDM4E | |
| SCHEMBL618600 | 0.84 | EPHX1 (0.44) | EPHX1KDM4CHPGDKMT2AALDH1A1 | |
| SCHEMBL14214964 | 0.82 | EPHX1 (0.49) | EPHX1KDM4CHPGDKMT2AALDH1A1 | |
| SCHEMBL6262428 | 0.80 | EPHX1 (0.42) | EPHX1KDM4CKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1908722 | 0.80 | EPHX1 (0.42) | EPHX1KDM4CKDM4EKMT2AALDH1A1 | |
| SCHEMBL14559564 | 0.80 | EPHX1 (0.42) | EPHX1KDM4CKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL969173 | 0.80 | NPC1 (0.46) | EPHX1KDM4CKMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL15878571 | 0.79 | EPHX1 (0.41) | EPHX1KDM4CALDH1A1SMN1; SMN2MMP1 | |
| Hydrochloric Acid SCHEMBL4519956 | 0.79 | EPHX1 (0.41) | EPHX1KDM4CALDH1A1SMN1; SMN2MMP1 | |
| SCHEMBL16890324 | 0.78 | EPHX1 (0.52) | EPHX1HPGDL3MBTL1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654977-B2 | Underwater self-healable materials, methods of making thereof, and products comprising same | CITY UNIVERSITY OF HONG KONG (HK) | 2020-05-19 | — | — | US | disclosed |
| US-9688715-B2 | Synthetic pGpG analogs, methods of preparation and methods of use | Temple University—Of the Commonwealth System of Higher Education (US) | 2017-06-27 | — | — | US | disclosed |
| US-9242984-B2 | Pyrazolyl derivatives as Syk inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-01-26 | — | — | US | disclosed |
| US-20150191461-A1 | PYRAZOLYL DERIVATIVES AS SYK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-07-09 | — | — | US | disclosed |
| US-20150175649-A1 | SYNTHETIC pGpG ANALOGS, METHODS OF PREPARATION AND METHODS OF USE | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2015-06-25 | — | — | US | disclosed |
| US-8137688-B2 | Hydroxyphenyl cross-linked macromolecular network and applications thereof | THE CLEVELAND CLINIC FOUNDATION (US) | 2012-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191461-A1 | PYRAZOLYL DERIVATIVES AS SYK INHIBITORS | SYK, BTK, LCK | EPHX1 1507/4885KDM4C 1807/4885HPGD 1424/4885 |
| US-20150175649-A1 | SYNTHETIC pGpG ANALOGS, METHODS OF PREPARATION AND METHODS OF USE | MRPL21, PGLS, CFTR | EPHX1 1818/4885KDM4C 2702/4885HPGD 341/4885 |
| US-10654977-B2 | Underwater self-healable materials, methods of making thereof, and products comprising same | SHH, GLI1, AQP1 | EPHX1 302/4885KDM4C 1254/4885HPGD 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.