Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 4/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7241872 | 0.83 | CACNA1H (0.34) | CACNA1HKDM4EHPGDGAAALDH1A1 | |
| SCHEMBL9198054 | 0.81 | CACNA1H (0.34) | CACNA1HKDM4EHPGDMAPTPOLB | |
| SCHEMBL9196734 | 0.69 | VCAM1 (0.33) | CACNA1HKDM4EHPGDMAPTPOLB | |
| SCHEMBL9283765 | 0.68 | VCAM1 (0.35) | CACNA1HKDM4EHPGDMAPTPOLB | |
| SCHEMBL8481047 | 0.68 | CSNK2A1 (0.43) | CACNA1HCSNK2A1KDM4EHPGDMAPT | |
| SCHEMBL20623233 | 0.63 | CACNA1H (0.62) | CACNA1HCACNA1GCACNA1C | |
| SCHEMBL7002106 | 0.62 | RIPK1 (0.55) | CACNA1HCSNK2A1KDM4EHPGDMAPT | |
| SCHEMBL11086137 | 0.61 | CSNK2A1 (0.54) | CSNK2A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL11086143 | 0.61 | CSNK2A1 (0.54) | CSNK2A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7087257 | 0.61 | MAPT (0.59) | CSNK2A1KDM4EHPGDMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667862-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |