Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208251 | 0.92 | PRSS1 (0.33) | CYP3A4MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL9197566 | 0.90 | MAPT (0.35) | CYP3A4MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9204247 | 0.89 | CYP3A4 (0.37) | CYP3A4MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL9203046 | 0.87 | CYP4F2 (0.38) | CYP3A4MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL9206935 | 0.86 | SLC7A5 (0.35) | CYP3A4MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL9206870 | 0.86 | PTGS2 (0.38) | CYP3A4MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL9206999 | 0.84 | HPGD (0.40) | CYP3A4MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL9203895 | 0.81 | MEN1 (0.51) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL9198798 | 0.80 | HDAC8 (0.40) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9206588 | 0.79 | CYP11B1 (0.34) | CYP3A4KMT2AALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |