Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204247 | 0.88 | CYP3A4 (0.37) | ALDH1A1OPRD1CYP3A4OPRM1MEN1 | |
| SCHEMBL9198641 | 0.86 | NR1H4 (0.36) | SLC7A5ALDH1A1NR1H4CYP3A4KMT2A | |
| SCHEMBL9205183 | 0.86 | CYP3A4 (0.34) | ALDH1A1OPRD1CYP3A4OPRM1MEN1 | |
| SCHEMBL9206870 | 0.85 | PTGS2 (0.38) | ALDH1A1OPRD1CYP3A4OPRM1MEN1 | |
| SCHEMBL9208251 | 0.84 | PRSS1 (0.33) | ALDH1A1OPRD1CYP3A4OPRM1MEN1 | |
| SCHEMBL9197566 | 0.82 | MAPT (0.35) | ALDH1A1CYP3A4MEN1KMT2AHPGD | |
| SCHEMBL9199128 | 0.82 | HSD17B2 (0.40) | ALDH1A1CYP3A4TDP1L3MBTL1KDM4E | |
| SCHEMBL9198805 | 0.81 | EPHX2 (0.38) | ALDH1A1NR1H4MEN1KMT2AEPHX2 | |
| SCHEMBL9202154 | 0.80 | ALDH1A1 (0.41) | ALDH1A1CYP3A4MEN1KMT2ATDP1 | |
| SCHEMBL9200672 | 0.73 | CYP4F2 (0.39) | ALDH1A1CYP3A4KMT2ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |