SCHEMBL9205240

SCHEMBL9205240

CCC(CBr)CS(N)(=O)=O

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL224527 0.85 CA1 (0.34) CA12CA1CA2CA7CA14
SCHEMBL28145600 0.82 CA1 (0.33) CA12CA1CA2CA7CA14
SCHEMBL9203677 0.76 ALDH1A1 (0.39) CA12CA1CA2CA7CA14
SCHEMBL28163256 0.76 CA2 (0.48) CA12CA1CA2CA7CA14
SCHEMBL3795708 0.73 ALDH1A1 (0.52) CA12CA1CA2CA7CA14
SCHEMBL17542473 0.71 CA12 (0.31) CA12CA1CA2CA7CA14
SCHEMBL17542521 0.71 CA12 (0.31) CA12CA1CA2CA7CA14
SCHEMBL17558374 0.71 CA12 (0.31) CA12CA1CA2CA7CA14
SCHEMBL5130601 0.70 CA2 (0.52) CA12CA1CA2CA7CA14
SCHEMBL30803995 0.70 CA2 (0.44) CA12CA1CA2CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1032361-C Imidazopyridazines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1996-07-24 CN disclosed
EP-0381132-B1 Imidazopyridazines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-03-08 EP disclosed
EP-0637301-A1 FUNGICIDAL OXAZOLIDINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-02-08 EP disclosed
US-5202324-A Bronchodilators TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-04-13 US disclosed
US-5155108-A Imidazopyridazines and use as antiasthmatic agents TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-13 US disclosed
CN-1047290-A Imidazopyridazine and preparation thereof and anticaustic TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1990-11-28 CN disclosed
EP-0381132-A1 Imidazopyridazines, their production and use Takeda Chemical Industries, Ltd. (JP) 1990-08-08 EP disclosed