Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 20/20 | 0.85 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sezolamide SCHEMBL637480 | 0.92 | CA2 (1.00) | CA2CA12CA1CA3AR | |
| Sezolamide SCHEMBL6086814 | 0.92 | CA2 (1.00) | CA2CA12CA1CA3AR | |
| Sezolamide SCHEMBL9879354 | 0.92 | CA2 (1.00) | CA2CA12CA1CA3AR | |
| Sezolamide SCHEMBL6085905 | 0.91 | CA2 (1.00) | CA2 | |
| Sezolamide SCHEMBL668227 | 0.91 | CA2 (1.00) | CA2 | |
| Sezolamide SCHEMBL8128967 | 0.90 | CA2 (0.98) | CA2 | |
| SCHEMBL19826857 | 0.86 | CA2 (1.00) | CA2CA12CA1CA3AR | |
| SCHEMBL10513416 | 0.86 | CA2 (1.00) | CA2CA12CA1CA3AR | |
| Hydrochloric Acid SCHEMBL10513807 | 0.82 | CA2 (1.00) | CA2 | |
| SCHEMBL10515039 | 0.81 | CA2 (0.69) | CA2CA12CA1CA3AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411704-B1 | Substituted aromatic sulfonamides as antiglaucoma agents | MERCK & CO INC (US) | 1995-01-11 | — | — | EP | claimed |
| EP-0411704-A1 | Substituted aromatic sulfonamides as antiglaucoma agents | MERCK & CO. INC. (US) | 1991-02-06 | — | — | EP | claimed |
| EP-0679156-A4 | — | UNIV FLORIDA STATE (US) | 1995-12-06 | — | — | EP | disclosed |
| EP-0679156-A1 | PROCESS FOR THE PREPARATION OF 10-DESACETOXYBACCATIN III | FLORIDA STATE UNIVERSITY (US) | 1995-11-02 | — | — | EP | disclosed |
| EP-0411704-B1 | Substituted aromatic sulfonamides as antiglaucoma agents | MERCK & CO INC (US) | 1995-01-11 | — | — | EP | disclosed |
| WO-1994015929-A1 | PROCESS FOR THE PREPARATION OF 10-DESACETOXYBACCATIN III | FLORIDA STATE UNIVERSITY (US) | 1994-07-21 | — | — | WO | disclosed |
| US-5120757-A | SUBSTITUTED AROMATIC SULFONAMIDES AS ANTIGLAUCOMA AGENTS | MERCK & CO., INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0411704-A1 | Substituted aromatic sulfonamides as antiglaucoma agents | MERCK & CO. INC. (US) | 1991-02-06 | — | — | EP | disclosed |