Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 15/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 15/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 15/20 | 0.67 |
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9212442 | 0.98 | ADRA1D (0.68) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| SCHEMBL9206883 | 0.92 | ADRA1D (0.67) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9214071 | 0.91 | ADRA1D (0.69) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| SCHEMBL9205140 | 0.91 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| SCHEMBL9204524 | 0.88 | ADRA1D (0.62) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| SCHEMBL9204173 | 0.86 | ADRA1D (0.60) | ADRA1DADRA1AADRA1B | |
| SCHEMBL9205957 | 0.86 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| SCHEMBL9214181 | 0.85 | CA1 (0.59) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| SCHEMBL9207882 | 0.85 | CA1 (0.59) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 | |
| SCHEMBL9204097 | 0.84 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BHTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520674-B1 | Antipsychotic benzodioxan derivatives | AMERICAN HOME PROD (US) | 1995-08-16 | — | — | EP | claimed |
| US-5126366-A | Antidepressants, antipsychotics, anxiolytic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-30 | — | — | US | claimed |
| EP-0520674-B1 | Antipsychotic benzodioxan derivatives | AMERICAN HOME PROD (US) | 1995-08-16 | — | — | EP | disclosed |
| EP-0520674-A1 | Antipsychotic benzodioxan derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-12-30 | — | — | EP | disclosed |
| US-5126366-A | Antidepressants, antipsychotics, anxiolytic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-30 | — | — | US | disclosed |