Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209437 | 0.95 | OPRM1 (0.42) | DNM1TSHRTHRBMEN1KMT2A | |
| SCHEMBL9205665 | 0.95 | OPRM1 (0.42) | DNM1TSHRTHRBMEN1KMT2A | |
| SCHEMBL9203784 | 0.95 | OPRM1 (0.42) | DNM1TSHRTHRBMEN1KMT2A | |
| SCHEMBL9212803 | 0.93 | OPRM1 (0.44) | DNM1TSHRTHRBMEN1KMT2A | |
| SCHEMBL9207705 | 0.91 | OPRM1 (0.42) | DNM1TSHRTHRBOPRM1SPHK1 | |
| SCHEMBL9213128 | 0.91 | OPRM1 (0.42) | DNM1TSHRTHRBOPRM1SPHK1 | |
| SCHEMBL9205128 | 0.86 | OPRM1 (0.42) | DNM1TSHRTHRBOPRM1SPHK1 | |
| SCHEMBL9214860 | 0.86 | OPRM1 (0.42) | DNM1TSHRTHRBOPRM1SPHK1 | |
| SCHEMBL9204299 | 0.84 | FAAH (0.44) | MEN1KMT2ALMNAUSP2TP53 | |
| SCHEMBL9204294 | 0.84 | FAAH (0.44) | MEN1KMT2ALMNAUSP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |