Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202588 | 1.00 | SLC18A3 (0.51) | SLC18A3ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL9197533 | 0.82 | MEN1 (0.55) | SLC18A3ALDH1A1KDM4EMAPTPARP1 | |
| SCHEMBL9203068 | 0.82 | MEN1 (0.55) | SLC18A3ALDH1A1KDM4EMAPTPARP1 | |
| SCHEMBL9196005 | 0.78 | MEN1 (0.52) | SLC18A3SIGMAR1DRD2HTR1ADRD4 | |
| SCHEMBL9197568 | 0.78 | NPC1 (0.52) | ALDH1A1KDM4EMAPTSIGMAR1DRD2 | |
| SCHEMBL9196003 | 0.78 | MEN1 (0.52) | SLC18A3SIGMAR1DRD2HTR1ADRD4 | |
| SCHEMBL9199454 | 0.77 | L3MBTL1 (0.54) | SLC18A3ALDH1A1KDM4EPARP1DRD2 | |
| SCHEMBL9202485 | 0.76 | MEN1 (0.44) | SLC18A3ALDH1A1KDM4EMAPTPARP1 | |
| SCHEMBL9202491 | 0.76 | MEN1 (0.44) | SLC18A3ALDH1A1KDM4EMAPTPARP1 | |
| SCHEMBL9196288 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MAPTPARP1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431580-B1 | Substituted cyclohexanols as central nervous system agents | WARNER LAMBERT CO (US) | 1995-03-08 | — | — | EP | claimed |