Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203752 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL9204333 | 0.85 | GRM1 (0.53) | SMN1; SMN2NPC1RAB9APKMKMT2A | |
| SCHEMBL9204272 | 0.82 | AKR1C3 (0.57) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL9203707 | 0.81 | DHODH (0.56) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL9202966 | 0.80 | RAB9A (0.49) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL9198091 | 0.79 | HTT (0.66) | SMN1; SMN2NPC1RAB9AHTTPKM | |
| SCHEMBL27522241 | 0.79 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL9204514 | 0.79 | TDP1 (0.51) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL9199984 | 0.77 | TDP1 (0.54) | HTTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9202946 | 0.77 | KMT2A (0.51) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |