Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201424 | 0.87 | LMNA (0.49) | HTTLMNAGAAKMT2AKCNK3 | |
| SCHEMBL9203707 | 0.86 | DHODH (0.56) | HTTLMNAGAAKMT2AKCNK3 | |
| SCHEMBL9204465 | 0.85 | F2R (0.52) | HTTLMNAGAAKMT2ANPC1 | |
| SCHEMBL9202946 | 0.85 | KMT2A (0.51) | HTTLMNAGAAKMT2ANPC1 | |
| SCHEMBL9199984 | 0.85 | TDP1 (0.54) | HTTLMNAGAAKMT2AKCNK3 | |
| SCHEMBL9199688 | 0.83 | KCNK3 (0.65) | KMT2AKCNK3KCNK9NPC1RAB9A | |
| SCHEMBL22512393 | 0.80 | HTT (1.00) | HTTLMNAGAAKMT2AKCNK3 | |
| SCHEMBL9200578 | 0.80 | HPGD (0.49) | HTTLMNAGAAKMT2ANPC1 | |
| SCHEMBL9205680 | 0.79 | SMN1; SMN2 (0.53) | HTTLMNAKMT2APKMNPC1 | |
| SCHEMBL9199865 | 0.78 | PKM (0.53) | LMNAKMT2APKMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |