SCHEMBL92058

SCHEMBL92058

COC(=O)C(F)(F)C(=O)F

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.37
ALDH1A1 P00352 3/20 0.36
KCNN4 O15554 1/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
KMT2A Q03164 1/20 0.33
SRC P12931 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2580230 0.85 DGAT1 (0.42) DGAT1ALDH1A1KCNN4MAPTMEN1
SCHEMBL16115556 0.83 DGAT1 (0.37) DGAT1ALDH1A1KCNN4MAPTSRC
SCHEMBL9569881 0.80 DGAT1 (0.39) DGAT1ALDH1A1KCNN4MAPTMEN1
SCHEMBL5704803 0.79 DGAT1 (0.34) DGAT1ALDH1A1KCNN4MAPT
SCHEMBL1366206 0.78 ALDH1A1 (0.41) DGAT1ALDH1A1KCNN4MAPTSRC
SCHEMBL21393608 0.78 KCNN4 (0.38) DGAT1ALDH1A1KCNN4MAPTMEN1
SCHEMBL10825857 0.76 DGAT1 (0.36) DGAT1ALDH1A1KCNN4MAPT
SCHEMBL17057345 0.76 DGAT1 (0.36) DGAT1ALDH1A1KCNN4
Fluoride SCHEMBL11201232 0.76 KCNN4 (0.37) DGAT1ALDH1A1KCNN4MEN1KMT2A
Hydrochloric Acid SCHEMBL28253420 0.76 ALDH1A1 (0.39) DGAT1ALDH1A1KCNN4MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5206422-A Process for preparation of fluorinated carbonyl compounds THE DOW CHEMICAL COMPANY (US) 1993-04-27 US claimed
US-12391797-B2 Fluoropolyether group containing compound and method for producing the same DAIKIN INDUSTRIES, LTD. (JP) 2025-08-19 US disclosed
EP-4029898-B1 FLUOROPOLYETHER GROUP CONTAINING COMPOUND AND METHOD FOR PRODUCING SAME DAIKIN IND LTD (JP) 2025-08-06 EP disclosed
WO-2025033021-A1 FLUORINE-BASED LUBRICANT, ELECTRODE, AND SECONDARY BATTERY トヨタ自動車株式会社 2025-02-13 WO disclosed
WO-2023235189-A1 BIFUNCTIONAL PERFLUOROPOLYETHER COMPOSITIONS BASED ON HEXAFLUOROPROPYLENE OXIDE, PURIFICATION, AND USES THEREOF VISTASOL TECHNOLOGIES, LLC (US) 2023-12-07 WO disclosed
WO-2023157862-A1 METHOD FOR PRODUCING FLUOROETHER ダイキン工業株式会社 2023-08-24 WO disclosed
CN-110770200-B Process for preparing polyfluorinated allyl ethers and compounds related thereto 3M创新有限公司 2022-10-04 CN disclosed
US-20220235177-A1 FLUOROPOLYETHER GROUP CONTAINING COMPOUND AND METHOD FOR PRODUCING THE SAME DAIKIN INDUSTRIES, LTD. (JP) 2022-07-28 US disclosed
EP-4029898-A1 FLUOROPOLYETHER GROUP CONTAINING COMPOUND AND METHOD FOR PRODUCING SAME Daikin Industries, Ltd. (JP) 2022-07-20 EP disclosed
CN-114402011-A Fluorinated polyether-based compound and method for producing same 大金工业株式会社 2022-04-26 CN disclosed
US-4401829-A Process for the preparation of perfluorinated carboxylic acid fluorides HOECHST AKTIENGESELLSCHAFT (DE) 1983-08-30 US disclosed
EP-0048544-B1 PREPARATION OF DIFLUOROMALONYL FLUORIDE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-27 EP disclosed
US-4357282-A CONTACTING A FLUORINATED METHYL OR ETHYL EHTER HAVING A METHOXYLATED CARBON ATOM WITH A LEWIS ACID CATALYST ACYLATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-11-02 US disclosed
US-4349650-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-14 US disclosed
EP-0048544-A1 Preparation of difluoromalonyl fluoride E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-03-31 EP disclosed
US-4316986-A Preparation of difluoromalonyl fluoride E. I. DUPONT DE NEMOURS & COMPANY (US) 1982-02-23 US disclosed
US-4292449-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-09-29 US disclosed
US-4275225-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-23 US disclosed
US-4273729-A CARBONYL OR SULFONYL FLUORIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed
US-4273728-A NITRILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12391797-B2 Fluoropolyether group containing compound and method for producing the same AFF4, AFF1, AFF2 DGAT1 3700/4885ALDH1A1 358/4885KCNN4 2055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.