Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH4 | P08319 | 1/20 | 0.43 |
| ▸ | ADH7 | P40394 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29107020 | 0.98 | ALDH1A1 (0.56) | ALDH1A1TSHRCYP3A4ANPEPERAP2 | |
| SCHEMBL9202558 | 0.96 | ALDH1A1 (0.54) | ALDH1A1TSHRCYP3A4ANPEPERAP2 | |
| SCHEMBL26741304 | 0.95 | TSHR (0.52) | ALDH1A1TSHRCYP3A4ANPEPERAP2 | |
| SCHEMBL26741197 | 0.95 | TSHR (0.52) | ALDH1A1TSHRCYP3A4ANPEPERAP2 | |
| SCHEMBL22861921 | 0.92 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4ANPEPERAP2 | |
| SCHEMBL11663392 | 0.91 | ALDH1A1 (0.72) | ALDH1A1TSHRCYP3A4ANPEPERAP2 | |
| SCHEMBL9204886 | 0.91 | ALDH1A1 (0.72) | ALDH1A1TSHRCYP3A4ANPEPERAP2 | |
| SCHEMBL28697359 | 0.91 | ALDH1A1 (0.72) | ALDH1A1TSHRCYP3A4ANPEPERAP2 | |
| SCHEMBL9174256 | 0.91 | ALDH1A1 (0.72) | ALDH1A1TSHRCYP3A4ANPEPERAP2 | |
| SCHEMBL2949453 | 0.91 | ALDH1A1 (0.72) | ALDH1A1TSHRCYP3A4ANPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |