SCHEMBL9206533

SCHEMBL9206533

CC1=C(CCC(C)/C=C\C#N)C(C)(C)CCC1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
RARB P10826 2/20 0.36
RARG P13631 2/20 0.36
RXRA P19793 2/20 0.36
RARA P10276 1/20 0.36
TRPA1 O75762 5/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.34
ALOX5 P09917 1/20 0.33
ALOX15 P16050 1/20 0.33
PDCD1 Q15116 1/20 0.32
ACE2 Q9BYF1 1/20 0.32
CD274 Q9NZQ7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9205545 1.00 ALDH1A1 (0.36) ALDH1A1GAAMAPTNPSR1RARB
SCHEMBL23903751 0.82 ALDH1A1 (0.40) ALDH1A1GAAMAPTNPSR1RARB
SCHEMBL4913470 0.79 ALDH1A1 (0.42) ALDH1A1GAAMAPTNPSR1RARB
SCHEMBL454132 0.79 ALDH1A1 (0.42) ALDH1A1GAAMAPTNPSR1RARB
SCHEMBL3146722 0.79 ALDH1A1 (0.42) ALDH1A1GAAMAPTNPSR1RARB
SCHEMBL9201572 0.77 CYP1A2 (0.49) ALDH1A1GAAMAPTNPSR1RARB
SCHEMBL9205369 0.77 CYP1A2 (0.49) ALDH1A1GAAMAPTNPSR1RARB
SCHEMBL18084338 0.76 TRPA1 (0.43) ALDH1A1GAAMAPTNPSR1RARB
SCHEMBL18727653 0.76 ALDH1A1 (0.43) ALDH1A1GAAMAPTNPSR1RARB
SCHEMBL9202931 0.75 RARB (0.41) ALDH1A1GAAMAPTNPSR1RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0525579-B1 Process for preparing substituted hexemic acids GIVAUDAN ROURE INT (CH) 1995-09-20 EP disclosed
US-5292902-A Process for the manufacture of odorants and intermediates used therein GIVAUDAN-ROURE CORPORATION (US) 1994-03-08 US disclosed
EP-0525579-A2 Process for preparing substituted hexemic acids GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1993-02-03 EP disclosed