Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650141 | 0.85 | CYP19A1 (0.35) | MAPTLMNACYP19A1POLBKMT2A | |
| SCHEMBL6194176 | 0.84 | TDP1 (0.38) | MAPTCYP19A1POLBKMT2AMEN1 | |
| SCHEMBL15208829 | 0.84 | POLB (0.34) | MAPTCYP19A1POLBALDH1A1KMT2A | |
| SCHEMBL6191703 | 0.84 | AHR (0.38) | MAPTLMNACYP19A1POLBMAPK1 | |
| SCHEMBL5631988 | 0.84 | HPRT1 (0.47) | MAPTLMNAPOLBMAPK1ALDH1A1 | |
| SCHEMBL3296222 | 0.84 | CRHBP (0.49) | MAPTLMNACYP19A1POLBMAPK1 | |
| SCHEMBL6190789 | 0.83 | LMNA (0.52) | MAPTLMNACYP19A1POLBALDH1A1 | |
| SCHEMBL15639645 | 0.81 | CA12 (0.43) | CA12CA1CA2CA9CA14 | |
| SCHEMBL15640033 | 0.81 | CA12 (0.43) | CA12CA1CA2CA9CA14 | |
| SCHEMBL28952404 | 0.81 | HSD17B10 (0.47) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655064-A1 | CHROMOGENIC REAGENTS | THE UNIVERSITY OF LIVERPOOL (GB) | 1995-05-31 | — | — | EP | disclosed |
| WO-1994004539-A9 | CHROMOGENIC REAGENTS | — | 1995-02-23 | — | — | WO | disclosed |
| WO-1994004539-A1 | CHROMOGENIC REAGENTS | THE UNIVERSITY OF LIVERPOOL (GB) | 1994-03-03 | — | — | WO | disclosed |