Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203771 | 0.82 | RAB9A (0.42) | ACHERAB9ANPC1MAPT | |
| SCHEMBL9203779 | 0.82 | RAB9A (0.42) | ACHERAB9ANPC1MAPT | |
| SCHEMBL9200039 | 0.81 | KMT2A (0.42) | HTTGAAMAPTSMN1; SMN2 | |
| SCHEMBL9200045 | 0.81 | KMT2A (0.42) | HTTGAAMAPTSMN1; SMN2 | |
| SCHEMBL9201969 | 0.81 | PTPN1 (0.38) | BRD4MAPK1MAOBLMNAGAA | |
| SCHEMBL9201770 | 0.81 | SLC6A2 (0.37) | MAPK1MAOBLMNAGAAL3MBTL1 | |
| SCHEMBL9200269 | 0.81 | L3MBTL1 (0.35) | HPGDRAB9ANPC1GRM5BRD4 | |
| SCHEMBL9201778 | 0.81 | SLC6A2 (0.37) | MAPK1MAOBLMNAGAAL3MBTL1 | |
| SCHEMBL9200278 | 0.81 | L3MBTL1 (0.35) | HPGDRAB9ANPC1GRM5BRD4 | |
| SCHEMBL9201963 | 0.81 | PTPN1 (0.38) | BRD4MAPK1MAOBLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413668-B1 | New 2,3-dihydro-5-oxy-4,6,7-trimethylbenzofuranes 2-(RS)-substitutes, useful as antioxidizing pharmaceutical products having mucoregolating and anti-ischemic properties | FOSCAMA BIOMED CHIM FARMA (IT) | 1995-12-06 | — | — | EP | disclosed |
| US-5114966-A | Radical scavengers | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 1992-05-19 | — | — | US | disclosed |