Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203591 | 0.92 | KAT2B (0.51) | KAT2BMAPTAPAF1NPC1MITF | |
| SCHEMBL9206570 | 0.87 | TOP1 (0.53) | KAT2BKMT2ATOP1ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL9202443 | 0.86 | TOP1 (0.52) | KAT2BTOP1ADORA2AADORA1GAA | |
| SCHEMBL9202338 | 0.82 | SMN1; SMN2 (0.51) | MAPTAPAF1NPC1MITFNSD2 | |
| SCHEMBL9209216 | 0.78 | TOP1 (0.59) | KAT2BMAPTKMT2AMAPK1TERT | |
| SCHEMBL9200470 | 0.78 | HTT (0.48) | MAPTNSD2KMT2AMAPK1NPSR1 | |
| Hydrochloric Acid SCHEMBL9208228 | 0.77 | TOP1 (0.58) | KAT2BMAPTKMT2AMAPK1TERT | |
| Hydrochloric Acid SCHEMBL9205563 | 0.77 | HTT (0.47) | MAPTNSD2KMT2AMAPK1NPSR1 | |
| SCHEMBL9208748 | 0.76 | TOP2B (0.59) | MAPTAPAF1NPC1NSD2RAB9A | |
| SCHEMBL9676864 | 0.76 | KMT2A (0.39) | MAPTAPAF1NPC1MITFNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497809-B1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER MANNHEIM ITALIA (IT) | 1995-06-28 | — | — | EP | disclosed |
| US-5162320-A | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1992-11-10 | — | — | US | disclosed |
| EP-0497809-A1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES. | BOEHRINGER MANNHEIM ITALIA (IT) | 1992-08-12 | — | — | EP | disclosed |
| WO-1991006540-A1 | 1,4-BIS(ALKYLAMINO)-2,3-DIAZA-ANTHRACENE-9,10-DIONES | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1991-05-16 | — | — | WO | disclosed |