Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 12/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8508675 | 1.00 | EPHX1 (0.39) | EPHX1ALDH1A1TSHRNAAAADH1B | |
| SCHEMBL21310476 | 0.94 | EPHX1 (0.41) | EPHX1ALDH1A1TSHRNAAAADH1B | |
| SCHEMBL30142446 | 0.91 | TSHR (0.33) | TSHRADH1BADH1CADH1AADH7 | |
| SCHEMBL24426039 | 0.91 | ALDH1A1 (0.40) | EPHX1ALDH1A1TSHRNAAAADH1B | |
| SCHEMBL28149210 | 0.87 | TSHR (0.43) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL27523829 | 0.82 | OPRL1 (0.34) | — | |
| SCHEMBL18948680 | 0.82 | OPRL1 (0.34) | — | |
| SCHEMBL3443660 | 0.81 | EPHX1 (0.41) | EPHX1ALDH1A1TSHRNAAAADH1B | |
| SCHEMBL2733772 | 0.78 | ALDH1A1 (0.40) | EPHX1ALDH1A1TSHRNAAAADH1B | |
| SCHEMBL9801608 | 0.78 | NAAA (0.40) | EPHX1NAAAGBA1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |